Research and development technology of pharmaceutical intermediate process

The R & D and production of pharmaceutical intermediates is an industry with many barriers, which is by no means "a processing plant without technical content".
R & D and production enterprises need to provide the following technologies:

● directional nitrification Technology

Neutral acid nitrification (clean nitrification) is used to reduce cost, eliminate pollution and reach the level of green nitrification.

● high temperature and high pressure reaction technology

The equipment can be used to complete chemical processes such as condensation, polymerization, alkylation and hydrogenation.

● condensation technology

Through Mannich condensation and aldol aldehyde ketone condensation to obtain macromolecules, the selection of catalyst is a key technology.

● controlled oxidation technology

The oxidation of aliphatic aromatic compounds to acids is relatively easy, and its intermediate aromatic aldehydes are important intermediates of pharmaceuticals and pesticides.

● fluorination Technology

The introduction of fluoro group into organic intermediates and the synthesis of fluoride are important pharmaceutical intermediates. How to introduce fluorine into the matrix is an object of concern.

● hydrogenation reduction technology

Reduction technologies such as iron powder reduction and sodium sulfide reduction are seriously polluted. The selection and application of catalysts are the key to the success of hydrogenation reduction.

Invite biology to ensure the smooth transfer of process technology and production scale, and promote the project from the pre clinical stage to the commercialized stage. Always provide high-quality services for customers in all stages of clinical research, so as to shorten the cycle of drug research and development.